Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.63 |
| ▸ | ABL1 | P00519 | 3/20 | 0.54 |
| ▸ | RAF1 | P04049 | 3/20 | 0.54 |
| ▸ | LYN | P07948 | 3/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 2/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.54 |
| ▸ | EPHA3 | P29320 | 2/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086203 | 0.95 | MAPK14 (0.64) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4091569 | 0.89 | MAPK14 (0.59) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL5384018 | 0.87 | MAPK14 (0.50) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6801738 | 0.85 | MAPK14 (0.52) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4091873 | 0.83 | MAPK14 (0.81) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL6612084 | 0.83 | ABL1 (0.65) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4098327 | 0.81 | MAPK14 (0.81) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4087726 | 0.81 | MAPK14 (0.54) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4086422 | 0.80 | ABL1 (0.82) | MAPK14ABL1RAF1LYNMAPK9 | |
| SCHEMBL4085454 | 0.80 | MAPK14 (0.82) | MAPK14ABL1RAF1LYNMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040033222-A1 | Anticoagulant and fibrinolytic therapy uning p38 MAP kinase inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040033222-A1 | Anticoagulant and fibrinolytic therapy uning p38 MAP kinase inhibitors | TFPI2, TFPI, PLG | MAPK14 30/4885ABL1 2261/4885RAF1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.