SCHEMBL6802223

SCHEMBL6802223

CC(C)(C)OC(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)C(=O)Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.64
PTPRB P23467 14/20 0.64
CTSS P25774 4/20 0.55
CTSK P43235 3/20 0.55
CTSL P07711 1/20 0.55
CTSB P07858 1/20 0.55
BCL2 P10415 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6802214 1.00 HDAC8 (0.64) HDAC8PTPRBCTSSCTSKCTSL
SCHEMBL3486972 0.88 PTPRB (0.61) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL3486971 0.88 PTPRB (0.61) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL6803159 0.88 PTPRB (0.61) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL9610766 0.88 HDAC8 (0.72) HDAC8CTSSCTSKCTSLCTSB
SCHEMBL3944495 0.88 HDAC8 (0.72) HDAC8CTSSCTSKCTSLCTSB
SCHEMBL6796146 0.88 PTPRB (0.64) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL6796141 0.88 PTPRB (0.64) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL6800329 0.88 PTPRB (0.64) PTPRBCTSSCTSKCTSLCTSB
SCHEMBL28219054 0.87 HDAC8 (0.69) HDAC8PTPRBCTSSCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE HDAC8 3002/4885PTPRB 13/4885CTSS 1861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.