Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781114 | 0.86 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL6806109 | 0.82 | KMT2A (0.62) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL1262765 | 0.82 | KMT2A (0.62) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL27910734 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL6801477 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL29409923 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL6798596 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL1660934 | 0.81 | KMT2A (0.60) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL29843297 | 0.78 | KMT2A (0.68) | KMT2AMEN1NPSR1MAPTGAA | |
| SCHEMBL5364554 | 0.77 | MEN1 (0.56) | KMT2AMEN1NPSR1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040027821-A1 | Pyrazolone lanthanide complexes | ISIS INNOVATION LIMITED (GB) | 2004-02-12 | — | — | US | disclosed |
| WO-2002020692-A1 | PYRAZOLONE LANTHANIDE COMPLEXES | ISIS INNOVATION LIMITED (GB) | 2002-03-14 | — | — | WO | disclosed |