SCHEMBL6803118

SCHEMBL6803118

CNC(=O)[C@@H](C(=O)NCCc1ccc(NS(=O)(=O)O)cc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
PTPRB P23467 3/20 0.44
PTPN2 P17706 2/20 0.44
PTPN1 P18031 2/20 0.44
PTPRA P18433 1/20 0.44
PTPRC P08575 1/20 0.43
PTPRG P23470 1/20 0.43
ACP1 P24666 1/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA9 Q16790 1/20 0.43
EPHX1 P07099 1/20 0.43
OPRK1 P41145 1/20 0.42
GLI1 P08151 1/20 0.42
GLI2 P10070 1/20 0.42
CNR1 P21554 1/20 0.41
KDM4A O75164 1/20 0.41
GHSR Q92847 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6803123 1.00 POLB (0.48) POLBPTPRBPTPN2PTPN1PTPRA
SCHEMBL6803371 0.85 CNR1 (0.58) POLBCNR1
SCHEMBL6916253 0.76 CA1 (0.44) POLBCA1CA2CA12CA4
SCHEMBL3923645 0.76 PTPRB (0.60) PTPRBPTPN1
SCHEMBL3923639 0.76 PTPRB (0.60) PTPRBPTPN1
SCHEMBL3766090 0.75 PTPN1 (0.56) POLBPTPN1CA1CA2
SCHEMBL4151569 0.74 POLB (0.64) POLBCA2CA12CA9EPHX1
SCHEMBL468138 0.73 PTPRB (0.43) POLBPTPRBCNR1
SCHEMBL12470057 0.72 ACACB (0.50) PTPRBCA1CA2
SCHEMBL14861138 0.72 POLB (0.61) POLBCA2CA12CA9EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO claimed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US claimed
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE POLB 3615/4885PTPRB 13/4885PTPN2 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.