Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692442 | 0.90 | KDM4E (0.50) | KDM4EL3MBTL1ATMNFE2L2HDAC1 | |
| SCHEMBL679028 | 0.87 | KDM4E (0.44) | KDM4EL3MBTL1ATMNFE2L2HDAC1 | |
| SCHEMBL13444158 | 0.86 | KDM4E (0.49) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL10708645 | 0.85 | KDM4E (0.60) | KDM4EL3MBTL1ATMNFE2L2HDAC1 | |
| SCHEMBL13157274 | 0.85 | KDM4E (0.60) | KDM4EL3MBTL1ATMNFE2L2HDAC1 | |
| SCHEMBL10708650 | 0.85 | KDM4E (0.60) | KDM4EL3MBTL1ATMNFE2L2HDAC1 | |
| SCHEMBL13238008 | 0.85 | KDM4E (0.40) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL17001374 | 0.85 | AKR1C4 (0.42) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL17001376 | 0.85 | AKR1C4 (0.42) | KDM4EL3MBTL1ATMALDH1A1HPGD | |
| SCHEMBL17001375 | 0.85 | AKR1C4 (0.42) | KDM4EL3MBTL1ATMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053547-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | MERCK PATENT GMBH (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20110068304-A1 | Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof | MERCK PATENT GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-7834136-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2010-11-16 | — | — | US | disclosed |