Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806855 | 0.97 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6811557 | 0.95 | ITGAV (0.50) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6806820 | 0.95 | ITGAV (0.50) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6810582 | 0.95 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6807882 | 0.92 | ITGAV (0.47) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6800565 | 0.92 | ITGAV (0.50) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6810336 | 0.91 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6805574 | 0.91 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6806199 | 0.90 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGA2B | |
| SCHEMBL6805558 | 0.90 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142877-A1 | Ligands of the $g(a)v$g(b)6 integrin | MERCK PATENT GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142877-A1 | Ligands of the $g(a)v$g(b)6 integrin | ITGB6, ITGAV, ITGB1 | ITGAV 2/4885ITGB3 13/4885ITGB6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.