Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 4/20 | 0.65 |
| ▸ | AURKA | O14965 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.65 |
| ▸ | PARP1 | P09874 | 16/20 | 0.62 |
| ▸ | DHODH | Q02127 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806072 | 0.98 | AURKB (0.68) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6801867 | 0.95 | AURKB (0.67) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6809857 | 0.93 | AURKB (0.70) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6810671 | 0.91 | AURKB (0.63) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6806488 | 0.91 | PARP1 (0.61) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6589397 | 0.89 | AURKB (0.51) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6806368 | 0.89 | AURKB (0.49) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6805128 | 0.88 | AURKB (0.66) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6805804 | 0.87 | PARP1 (0.58) | AURKBAURKAKDRPARP1DHODH | |
| SCHEMBL6806881 | 0.87 | AURKB (0.61) | AURKBAURKAKDRPARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |