SCHEMBL6806439

SCHEMBL6806439

c1ccccc2ccccc2ccc1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.89
ALOX12 P18054 2/20 0.89
ALDH1A1 P00352 6/20 0.50
HSD17B10 Q99714 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
TSHR P16473 4/20 0.50
CYP1A2 P05177 3/20 0.44
CYP3A4 P08684 3/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA7 P43166 1/20 0.44
HPRT1 P00492 1/20 0.44
HPGD P15428 2/20 0.43
CA12 O43570 1/20 0.43
GLA P06280 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA14 Q9ULX7 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL1518058 1.00 CYP2A6 (0.89) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL29352674 1.00 CYP2A6 (0.89) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL30984504 1.00 CYP2A6 (0.89) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL11145450 0.95 CYP2A6 (0.80) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL10438031 0.95 CYP2A6 (0.80) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
SCHEMBL2637812 0.95 CYP2A6 (0.80) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL1330659 0.94 CYP2A6 (1.00) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL1331142 0.94 CYP2A6 (1.00) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL1332240 0.94 CYP2A6 (1.00) CYP2A6ALOX12ALDH1A1HSD17B10TDP1
Naphthalene SCHEMBL8613802 0.94 CYP2A6 (1.00) CYP2A6ALOX12ALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305769-B1 Emitting material and organic light emitting diode using the same LG CHEMICAL LTD (KR) 2012-09-19 EP disclosed
WO-2009066952-A1 MONOMER FOR PROTON-CONDUCTING POLYMER HAVING ACID GROUP IN SIDE CHAIN THEREOF, PROTON-CONDUCTING POLYMER PREPARED USING THE MONOMER, METHOD OF PREPARING THE PROTON-CONDUCTING POLYMER, ELECTROLYTE MEMBRANE COMPRISING THE PROTON-CONDUCTING POLYMER, AND MEMBRANE-ELECTRODE ASSEMBLY INCLUDING THE ELECTROLYTE DONGJIN SEMICHEM CO., LTD. (KR) 2009-05-28 WO disclosed
EP-1439885-A1 SIMPLIFIED SARCODICTYN DERIVATIVES AS ANTI-TUMOR AGENTS Pharmacia Italia S.p.A. (IT) 2004-07-28 EP disclosed
WO-2003024529-A1 SIMPLIFIED SARCODICTYN DERIVATIVES AS ANTI-TUMOR AGENTS PHARMACIA ITALIA SPA (IT) 2003-03-27 WO disclosed