Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 12/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805068 | 0.89 | CCR3 (0.51) | CCR3DRD3TMEM97CCR2DRD2 | |
| SCHEMBL6806794 | 0.87 | CCR3 (0.49) | CCR3DRD3TMEM97CCR2DRD2 | |
| SCHEMBL6807067 | 0.85 | SLC2A1 (0.44) | DRD3TMEM97CCR2DRD2DRD4 | |
| SCHEMBL6806579 | 0.84 | CCR3 (0.52) | CCR3DRD3TMEM97CCR2DRD2 | |
| SCHEMBL6811433 | 0.80 | DRD4 (0.39) | DRD3DRD2DRD4KCNH2 | |
| SCHEMBL6912325 | 0.79 | CCR3 (0.44) | CCR3DRD3TMEM97CCR2DRD2 | |
| SCHEMBL6802933 | 0.78 | SLC2A1 (0.44) | DRD3CCR2DRD2DRD4DRD1 | |
| SCHEMBL6802884 | 0.77 | CCR3 (0.53) | CCR3DRD3TMEM97CCR2DRD2 | |
| SCHEMBL6811161 | 0.75 | MAOB (0.42) | DRD3DRD2HTR1A | |
| SCHEMBL6802847 | 0.72 | CCR3 (0.47) | CCR3DRD3TMEM97CCR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072865-A1 | Aryl piperidine derivatives as inducers of ldl-receptor expression | SMITHKLINE BEECHAM CORPORATION | 2004-04-15 | — | — | US | claimed |
| US-20040072865-A1 | Aryl piperidine derivatives as inducers of ldl-receptor expression | SMITHKLINE BEECHAM CORPORATION | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072865-A1 | Aryl piperidine derivatives as inducers of ldl-receptor expression | NR1H2, NR1H3, NR1H4 | CCR3 290/4885DRD3 222/4885TMEM97 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.