Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808188 | 0.82 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL18192014 | 0.80 | RECQL (0.62) | KDM4EALDH1A1RAB9AHPGDMAPK1 | |
| SCHEMBL230403 | 0.80 | KDM4E (0.57) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL12648806 | 0.80 | MEN1 (0.57) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16692197 | 0.80 | MEN1 (0.57) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL6912526 | 0.79 | TLR8 (0.55) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL1171430 | 0.78 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL24206190 | 0.77 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL3714642 | 0.77 | PDE10A (0.56) | MEN1KMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL16692167 | 0.77 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113351-A2 | BIFUNCTIONAL AMINO-BORON LEWIS ACID - LEWIS BASE CATALYST | UNIVERSITY OF DURHAM (GB) | 2004-12-29 | — | — | WO | disclosed |