Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.49 |
| ▸ | HRAS | P01112 | 7/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809094 | 1.00 | SIRT2 (0.49) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6809101 | 0.90 | HRAS (0.53) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6809104 | 0.90 | HRAS (0.53) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6813614 | 0.88 | SIRT2 (0.49) | SIRT2HRAS | |
| SCHEMBL6813616 | 0.88 | SIRT2 (0.49) | SIRT2HRAS | |
| SCHEMBL6813557 | 0.88 | SIRT2 (0.52) | SIRT2HRAS | |
| SCHEMBL6812563 | 0.86 | HRAS (0.48) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6812555 | 0.86 | HRAS (0.48) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6812628 | 0.86 | HRAS (0.53) | SIRT2HRASFNTAFNTB | |
| SCHEMBL6812617 | 0.86 | HRAS (0.53) | SIRT2HRASFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951471-B1 | CYCLOALKYL INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER LAMBERT CO (US) | 2004-03-17 | — | — | EP | disclosed |