Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL6813805 | 0.88 | APP (0.56) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| Acetic Acid SCHEMBL233001 | 0.86 | APP (0.59) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| T-Butylacetic Acid SCHEMBL6809308 | 0.86 | APP (0.73) | APPCYP1A2KMT2AMEN1POLB | |
| Bromoacetic Acid SCHEMBL1896728 | 0.85 | APP (0.56) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| Butyric Acid SCHEMBL381473 | 0.84 | APP (0.52) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| Sarcosine SCHEMBL9810246 | 0.83 | APP (0.51) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| Levulinic Acid SCHEMBL8512312 | 0.83 | APP (0.51) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| SCHEMBL8067 | 0.83 | APP (0.65) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| SCHEMBL6813575 | 0.83 | APP (0.56) | APPCYP1A2KMT2ARAB9AALDH1A1 | |
| SCHEMBL1096453 | 0.82 | APP (0.63) | APPCYP1A2KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| US-20020177180-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |