Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583065 | 0.88 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL6581549 | 0.88 | TRPV1 (0.78) | TRPV1KDR | |
| SCHEMBL6584664 | 0.87 | TRPV1 (1.00) | TRPV1KDR | |
| SCHEMBL6586681 | 0.82 | TRPV1 (0.70) | TRPV1KDR | |
| SCHEMBL462753 | 0.81 | KDR (0.76) | TRPV1KDR | |
| SCHEMBL18615549 | 0.79 | TRPV1 (0.72) | TRPV1KDR | |
| SCHEMBL19668250 | 0.79 | KDR (0.78) | TRPV1KDR | |
| SCHEMBL19677976 | 0.78 | KDR (0.88) | TRPV1KDR | |
| SCHEMBL20357554 | 0.78 | TRPV1 (0.71) | TRPV1KDR | |
| SCHEMBL118026 | 0.78 | KDR (1.00) | TRPV1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259875-A1 | Amine derivatives | BAYER HEALTHCARE AG (DE) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259875-A1 | Amine derivatives | AVPR1A, GRIN1, OPRL1 | TRPV1 14/4885KDR 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.