Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 4/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.44 |
| ▸ | NMBR | P28336 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710727 | 1.00 | HRAS (0.51) | HRASSIRT2NMBRSYKFNTA | |
| SCHEMBL6813733 | 0.92 | SIRT2 (0.47) | HRASSIRT2NMBRSYK | |
| SCHEMBL6813730 | 0.92 | SIRT2 (0.47) | HRASSIRT2NMBRSYK | |
| SCHEMBL7712921 | 0.90 | SIRT2 (0.48) | HRASSIRT2NMBRSYK | |
| SCHEMBL6810651 | 0.90 | SIRT2 (0.48) | HRASSIRT2NMBRSYK | |
| SCHEMBL6814437 | 0.86 | HRAS (0.52) | HRASSIRT2NMBR | |
| SCHEMBL6813616 | 0.82 | SIRT2 (0.49) | HRASSIRT2NMBR | |
| SCHEMBL6813614 | 0.82 | SIRT2 (0.49) | HRASSIRT2NMBR | |
| SCHEMBL7860870 | 0.79 | HRAS (0.59) | HRASFNTAFNTB | |
| SCHEMBL6812778 | 0.79 | HRAS (0.59) | HRASFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076663-B1 | FUNCTIONALIZED ALKYL AND ALKENYL SIDE CHAIN DERIVATIVES OF GLYCINAMIDES AS FARNESYL TRANSFERASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-02-18 | — | — | EP | disclosed |