Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 8/20 | 1.00 |
| ▸ | GRPR | P30550 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | BID | P55957 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809988 | 0.84 | NMBR (0.80) | NMBRGRPRBCHEITGB2ICAM1 | |
| SCHEMBL6181017 | 0.82 | NMBR (1.00) | NMBRGRPRBCHEITGB2ICAM1 | |
| SCHEMBL6180485 | 0.81 | NMBR (0.75) | NMBRGRPR | |
| SCHEMBL7671985 | 0.78 | NMBR (0.65) | NMBRGRPRBCHEITGB2ICAM1 | |
| SCHEMBL6181433 | 0.75 | NMBR (1.00) | NMBRGRPRBCHEITGB2ICAM1 | |
| SCHEMBL14571110 | 0.75 | NMBR (0.71) | NMBRMAPT | |
| SCHEMBL8574758 | 0.72 | NMBR (0.75) | NMBRGRPRBCHESSTR2 | |
| SCHEMBL3848227 | 0.71 | ITGB2 (0.61) | NMBRBCHEITGB2ICAM1ITGAL | |
| SCHEMBL3849151 | 0.71 | ITGB2 (0.61) | NMBRBCHEITGB2ICAM1ITGAL | |
| SCHEMBL3848230 | 0.71 | ITGB2 (0.61) | NMBRBCHEITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087561-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY LLC | 2004-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087561-A1 | Treatment of sexual dysfunction | BRS3, MME, ECE1 | NMBR 258/4885GRPR 199/4885BCHE 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.