Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 13/20 | 0.84 |
| ▸ | LPAR2 | Q9HBW0 | 9/20 | 0.84 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.84 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29026467 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL4247095 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL18444275 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL29026510 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL4483106 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL18444519 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL2379995 | 1.00 | LPAR3 (0.84) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL27619288 | 0.98 | LPAR3 (0.88) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL28711361 | 0.98 | LPAR3 (0.88) | LPAR3LPAR2LPAR1LPAR5MEN1 | |
| SCHEMBL28936054 | 0.98 | LPAR3 (0.88) | LPAR3LPAR2LPAR1LPAR5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012838-A2 | COMPOUNDS WHICH MODULATE THE ACTIVITY OF AN LPA RECEPTOR | ATAIRGIN TECHNOLOGIES, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| EP-1024812-A4 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | SKY HIGH LLC (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1069895-A4 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | LXR BIOTECHNOLOGY INC (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001012838-A2 | COMPOUNDS WHICH MODULATE THE ACTIVITY OF AN LPA RECEPTOR | ATAIRGIN TECHNOLOGIES, INC. (US) | 2001-02-22 | — | — | WO | disclosed |
| EP-1069895-A2 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | LXR BIOTECHNOLOGY INC. (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1024812-A1 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | LXR BIOTECHNOLOGY INC. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999047101-A2 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | LXR BIOTECHNOLOGY, INC. (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1998041213-A1 | COMPOSITIONS CONTAINING LYSOPHOSPHOTIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | LXR BIOTECHNOLOGY INC. (US) | 1998-09-24 | — | — | WO | disclosed |