Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603053 | 0.92 | MEN1 (0.56) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17426920 | 0.85 | MAPK1 (0.57) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17981317 | 0.85 | MAPK1 (0.61) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16092693 | 0.84 | MAPK1 (0.56) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17426919 | 0.84 | MAPK1 (0.56) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6513070 | 0.84 | MAPK1 (0.56) | ATMMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3601229 | 0.83 | KMT2A (0.68) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL25144640 | 0.82 | SMN1; SMN2 (0.47) | ATMSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL18942306 | 0.81 | SMN1; SMN2 (0.53) | ATMSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL18942220 | 0.81 | SMN1; SMN2 (0.53) | ATMSMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086097-B1 | SULFONYLBENZENE COMPOUNDS AS ANTI-INFLAMMATORY/ANALGESIC AGENTS | PFIZER (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1104760-B1 | Sulfamoylheteroaryl pyrazole compounds as anti-inflammatory/analgesic agents | PFIZER PROD INC (US) | 2003-03-12 | — | — | EP | disclosed |