Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1716282 | 1.00 | — | — | |
| Bicarbonate SCHEMBL9777799 | 1.00 | CA4 (0.55) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL890048 | 0.95 | — | — | |
| Bicarbonate SCHEMBL14562574 | 0.95 | — | — | |
| Bicarbonate SCHEMBL950160 | 0.94 | — | — | |
| Bicarbonate SCHEMBL154738 | 0.94 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL2402027 | 0.94 | — | — | |
| Bicarbonate SCHEMBL14562576 | 0.91 | CA4 (0.46) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL3686141 | 0.89 | — | — | |
| Bicarbonate SCHEMBL8712057 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113062006-A | Environment-friendly composite textile material and preparation method thereof | 邵阳阳光发品有限公司 | 2021-07-02 | — | — | CN | claimed |
| US-9718750-B2 | Method for selective and regenerative removal of acetaldehyde using thermally decomposed sodium aluminum carbonate hydroxide on alumina | UOP LLC (US) | 2017-08-01 | — | — | US | claimed |
| US-20170174594-A1 | METHOD FOR SELECTIVE AND REGENERATIVE REMOVAL OF ACETALDEHYDE USING THERMALLY DECOMPOSED SODIUM ALUMINUM CARBONATE HYDROXIDE ON ALUMINA | UOP LLC | 2017-06-22 | — | — | US | claimed |
| EP-0725625-B1 | GELATIN CAPSULE FILL ABLE TO FOAM | SCHERER CORP R P (US) | 2000-03-22 | — | — | EP | claimed |
| US-5888540-A | Pharmaceutical products | CATALENT PHARMA SOLUTIONS, INC. | 1999-03-30 | — | — | US | claimed |
| EP-0725626-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1996-08-14 | — | — | EP | claimed |
| EP-0725625-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | R.P. SCHERER CORPORATION (US) | 1996-08-14 | — | — | EP | claimed |
| US-5512300-A | Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms | WARNER-LAMBERT COMPANY (US) | 1996-04-30 | — | — | US | claimed |
| US-5480587-A | PAPER OR POLYMERS | ALUMINUM COMPANY OF AMERICA (US) | 1996-01-02 | — | — | US | claimed |
| WO-1995011667-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | R.P. SCHERER CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1995011668-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1995-05-04 | — | — | WO | claimed |
| EP-0377881-A1 | Materials for use as fire retardant additives | ALUMINUM COMPANY OF AMERICA (US) | 1990-07-18 | — | — | EP | claimed |
| EP-4469535-A1 | FIRE PROTECTION MATERIAL | Freudenberg-NOK General Partnership (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118434823-A | Fireproof material | 弗罗伊登贝格-诺克普通合伙公司 | 2024-08-02 | — | — | CN | disclosed |
| US-11846097-B2 | Fiber products having temperature control additives | KNAUF INSULATION, INC. (US) | 2023-12-19 | — | — | US | disclosed |
| WO-2023147012-A1 | FIRE PROTECTION MATERIAL | FREUDENBERG-NOK GENERAL PARTNERSHIP (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-1995011667-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | R.P. SCHERER CORPORATION (US) | 1995-05-04 | — | — | WO | disclosed |
| WO-1995011668-A1 | GELATIN CAPSULE FILL ABLE TO FOAM | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1995-05-04 | — | — | WO | disclosed |
| EP-0147167-A2 | Continuous process for neutralization of aluminate solution to form gels and appartatus therefor | ALUMINUM COMPANY OF AMERICA (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4151218-A | CONTAINING A RUBBER MODIFIER, AN AROMATIC BROMINE COMPOUND, A METAL OXIDE AND A SMOKE SUPPRESANT | MONSANTO COMPANY (US) | 1979-04-24 | — | — | US | disclosed |