Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.57 |
| ▸ | HTR2A | P28223 | 9/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6714378 | 0.94 | HTR2C (0.55) | HTR2CHTR2ARIPK1MEN1NPC1 | |
| SCHEMBL6713675 | 0.81 | HTR2A (0.62) | HTR2CHTR2AMEN1NPC1TP53 | |
| SCHEMBL6711017 | 0.81 | HTR2C (0.57) | HTR2CHTR2AMEN1PKMKMT2A | |
| SCHEMBL6712249 | 0.81 | HTR2A (0.57) | HTR2CHTR2ANPC1LMNATP53 | |
| SCHEMBL6715306 | 0.81 | HTR2A (0.61) | HTR2CHTR2AMEN1LMNAMAPT | |
| SCHEMBL6713879 | 0.80 | HTR2A (0.64) | HTR2CHTR2AMEN1NPC1MAPT | |
| SCHEMBL6712815 | 0.80 | HTR2A (0.64) | HTR2CHTR2AMEN1NPC1LMNA | |
| SCHEMBL6714604 | 0.80 | HTR2A (0.58) | HTR2CHTR2AMEN1NPC1LMNA | |
| SCHEMBL6714643 | 0.80 | HTR2A (0.60) | HTR2CHTR2AMEN1NPC1RAB9A | |
| SCHEMBL6715343 | 0.80 | HTR2A (0.69) | HTR2CHTR2AMEN1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734301-B2 | 5-HT LIGANDS USED TO TREAT CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2004-05-11 | — | — | US | claimed |