SCHEMBL6811022

SCHEMBL6811022

C=C(C)C(=O)Oc1ccc(/C=C/c2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.64
KMT2A Q03164 5/20 0.53
MEN1 O00255 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPT P10636 2/20 0.50
TRPA1 O75762 1/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
TTR P02766 1/20 0.50
TP53 P04637 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ATM Q13315 1/20 0.48
RAD51 Q06609 1/20 0.47
RELA Q04206 2/20 0.46
GLA P06280 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PPARA Q07869 3/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL544782 1.00 ELANE (0.64) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL8662820 0.94 ELANE (0.60) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL16182817 0.93 ELANE (0.57) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL16182754 0.93 ELANE (0.57) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL8835839 0.93 ELANE (0.57) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL8835845 0.93 ELANE (0.57) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL14275345 0.89 KMT2A (0.68) ELANEKMT2AMEN1MAPTKDM4E
SCHEMBL10102835 0.88 ELANE (0.55) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL16182982 0.88 KMT2A (0.53) ELANEKMT2AMEN1CYP3A4MAPT
SCHEMBL22245453 0.88 KMT2A (0.53) ELANEKMT2AMEN1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670506-B1 POLARIZER, POLARIZING PLATE AND PROCESS FOR PRODUCTION THEREOF NIPPON KAYAKU KK (JP) 2004-01-14 EP disclosed
EP-1275988-A2 Polarizing element, and polarizing plate Nippon Kayaku Kabushiki Kaisha (JP) 2003-01-15 EP disclosed
US-5706131-A NO STRETCHING NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-01-06 US disclosed
EP-0670506-A1 POLARIZER, POLARIZING PLATE AND PROCESS FOR PRODUCTION THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1995-09-06 EP disclosed