Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 16/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.57 |
| ▸ | HTR1B | P28222 | 10/20 | 0.57 |
| ▸ | HTR1A | P08908 | 8/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816730 | 0.92 | HTR1D (0.60) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL6811132 | 0.88 | HTR1D (0.74) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5090873 | 0.86 | HTR1D (0.59) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5097776 | 0.86 | HTR1D (0.61) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL6811202 | 0.85 | HTR1D (0.77) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5093545 | 0.84 | HTR1D (0.57) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5097758 | 0.84 | HTR1D (0.57) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5092305 | 0.83 | HTR1D (0.56) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5088691 | 0.83 | HTR1D (0.56) | HTR1DSLC6A4HTR1BHTR1ADRD2 | |
| SCHEMBL5098874 | 0.83 | HTR1D (0.56) | HTR1DSLC6A4HTR1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | HTR1D 124/4885SLC6A4 1958/4885HTR1B 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.