Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.82 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812347 | 1.00 | MAPT (0.82) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3861230 | 0.95 | MAPT (0.82) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3861723 | 0.95 | MAPT (0.82) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6812618 | 0.90 | MAPT (0.94) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6812622 | 0.90 | MAPT (0.94) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL27077145 | 0.90 | MAPT (1.00) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13743142 | 0.81 | MAPT (0.76) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL13714629 | 0.79 | MAPT (0.58) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7858387 | 0.78 | MAPT (1.00) | MAPTTAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL6811797 | 0.75 | MAPT (0.64) | MAPTTAAR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808309-B1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS S-ADENOSYLMETHIONINE DECARBOXYLASE (=SAMDC) INHIBITORS | NOVARTIS AG (CH) | 2004-10-06 | — | — | EP | disclosed |
| US-5840911-A | ANTIPROTOZOA, ANTITUMOR | NOVARTIS AG (CH) | 1998-11-24 | — | — | US | disclosed |