Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.51 |
| ▸ | HRAS | P01112 | 5/20 | 0.47 |
| ▸ | NMBR | P28336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812843 | 1.00 | SIRT2 (0.51) | SIRT2HRASNMBR | |
| SCHEMBL6813557 | 0.94 | SIRT2 (0.52) | SIRT2HRASNMBR | |
| SCHEMBL6812617 | 0.92 | HRAS (0.53) | SIRT2HRAS | |
| SCHEMBL6812628 | 0.92 | HRAS (0.53) | SIRT2HRAS | |
| SCHEMBL6809116 | 0.88 | HRAS (0.48) | SIRT2HRAS | |
| SCHEMBL6809100 | 0.88 | HRAS (0.48) | SIRT2HRAS | |
| SCHEMBL6809104 | 0.87 | HRAS (0.53) | SIRT2HRAS | |
| SCHEMBL6809101 | 0.87 | HRAS (0.53) | SIRT2HRAS | |
| SCHEMBL6817407 | 0.86 | HRAS (0.60) | SIRT2HRAS | |
| SCHEMBL6817402 | 0.86 | HRAS (0.60) | SIRT2HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951471-B1 | CYCLOALKYL INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER LAMBERT CO (US) | 2004-03-17 | — | — | EP | disclosed |