Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813137 | 1.00 | ADRB3 (0.71) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL3016909 | 0.91 | ADRB3 (0.75) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL3016912 | 0.91 | ADRB3 (0.75) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL6814880 | 0.89 | ADRB3 (0.73) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL6814868 | 0.89 | ADRB3 (0.73) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL6812818 | 0.89 | ADRB3 (0.68) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL6812830 | 0.89 | ADRB3 (0.68) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL13959128 | 0.83 | ADRB3 (1.00) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL3025239 | 0.83 | ADRB3 (1.00) | ADRB3ADRB2LMNACYP2D6HIF1A | |
| SCHEMBL2341389 | 0.83 | ADRB3 (1.00) | ADRB3ADRB2LMNACYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |