Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11152955 | 0.98 | POLB (0.47) | POLB | |
| Hydrochloric Acid SCHEMBL11155358 | 0.98 | POLB (0.47) | POLB | |
| Hydrochloric Acid SCHEMBL11152950 | 0.98 | POLB (0.47) | POLB | |
| Hydrochloric Acid SCHEMBL11152960 | 0.98 | POLB (0.47) | POLB | |
| Hydrochloric Acid SCHEMBL11155278 | 0.98 | POLB (0.47) | POLB | |
| SCHEMBL5530485 | 0.90 | POLB (0.57) | POLB | |
| SCHEMBL4816295 | 0.84 | — | — | |
| SCHEMBL6811466 | 0.83 | IGF1R (0.51) | — | |
| Bromide SCHEMBL10761472 | 0.82 | IGF1R (0.50) | — | |
| Hydrochloric Acid SCHEMBL11155631 | 0.82 | IGF1R (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101175724-B | pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-12-07 | — | — | CN | disclosed |
| CN-101175724-A | Pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2008-05-07 | — | — | CN | disclosed |
| EP-0937458-B1 | Pyrrolidine and piperidine derivatives | HOFFMANN LA ROCHE (CH) | 2004-12-29 | — | — | EP | disclosed |
| US-6153624-A | Pyrrolidine and piperidine derivatives and treatment of neurodegenerative disorders | HOFFMAN-LAROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |
| US-6015824-A | N-METHYL-D-ASPARTATE RECEPTOR ANTAGONISTS; ALZHEIMER*S DISEASE; BRAIN, NERVOUS SYSTEM, AND PYSCHOLOGICAL DISORDERS | HOFFMANN-LA ROCHE AG (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0937458-A2 | Pyrrolidine and piperidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-25 | — | — | EP | disclosed |