Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813595 | 1.00 | EPHX1 (0.43) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL16413070 | 0.88 | AAK1 (0.45) | ITGB3ITGA2BAAK1CTSLDPP4 | |
| SCHEMBL6809881 | 0.88 | DPP4 (0.52) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL6809878 | 0.88 | DPP4 (0.52) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL9099990 | 0.87 | AAK1 (0.40) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL9099994 | 0.87 | AAK1 (0.40) | HDAC4HDAC1HDAC6ITGB3ITGA2B | |
| SCHEMBL22501529 | 0.85 | EPHX1 (0.45) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL12463556 | 0.85 | EPHX1 (0.45) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL21647650 | 0.82 | EPHX1 (0.42) | EPHX1HDAC4HDAC1HDAC6ITGB3 | |
| SCHEMBL28526295 | 0.82 | EPHX1 (0.42) | EPHX1HDAC4HDAC1HDAC6ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110817-A1 | Dipeptidyl peptidase IV inhibiting fluorinated cyclic amides | PFIZER INC | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110817-A1 | Dipeptidyl peptidase IV inhibiting fluorinated cyclic amides | DPP4, ALPI, DPP7 | EPHX1 3198/4885HDAC4 327/4885HDAC1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.