Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146739 | 0.83 | MAPT (0.48) | HTTLMNAMAPK1RAB9APRSS1 | |
| SCHEMBL773681 | 0.82 | HTT (0.65) | PTPN1HTTLMNAMAPK1RAB9A | |
| SCHEMBL29620834 | 0.82 | HTT (0.65) | PTPN1HTTLMNAMAPK1RAB9A | |
| SCHEMBL11124534 | 0.81 | GSK3B (0.46) | PTPN1RAB9AGSK3BMEN1ALDH1A1 | |
| SCHEMBL16210170 | 0.79 | EPHX2 (0.51) | PTPN1HTTLMNAMAPK1RAB9A | |
| SCHEMBL32665368 | 0.78 | PTPN1 (0.46) | PTPN1HTTLMNAMAPK1RAB9A | |
| SCHEMBL6816782 | 0.77 | MAPT (0.49) | HTTLMNAMAPK1RAB9APRSS1 | |
| SCHEMBL3368165 | 0.77 | PTPN1 (0.57) | PTPN1HTTLMNAMAPK1RAB9A | |
| SCHEMBL366866 | 0.77 | PTPN1 (0.61) | PTPN1RAB9AGSK3BMEN1KMT2A | |
| SCHEMBL29628387 | 0.77 | PTPN1 (0.61) | PTPN1RAB9AGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |