Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 3/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | FER | P16591 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MARK3 | P27448 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813318 | 0.83 | AURKB (0.53) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6810849 | 0.83 | AURKB (0.51) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6392625 | 0.83 | AURKB (0.48) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6810640 | 0.81 | MAPT (0.53) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6392629 | 0.81 | PRKD3 (0.62) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6813584 | 0.80 | PIM1 (0.51) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6813639 | 0.80 | PRKD3 (0.50) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6813901 | 0.78 | PRKD3 (0.51) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6813646 | 0.74 | PRKD3 (0.50) | AURKBPRKD3MAP4K4RETPIM1 | |
| SCHEMBL6818052 | 0.72 | PRKD3 (0.49) | AURKBPRKD3MAP4K4RETPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017384-B1 | AZABENZIMIDAZOLE-BASED COMPOUNDS FOR MODULATING SERINE/THREONINE PROTEIN KINASE FUNCTION | ZENTARIS GMBH (DE) | 2004-11-10 | — | — | EP | disclosed |