Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.71 |
| ▸ | PPARG | P37231 | 9/20 | 0.71 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814407 | 0.90 | PPARA (0.68) | PPARAPPARGPPARDFFAR1LMNA | |
| SCHEMBL6813922 | 0.87 | PPARA (0.53) | PPARAPPARGPPARDFFAR1LMNA | |
| Hydrochloric Acid SCHEMBL6813448 | 0.87 | PPARA (0.67) | PPARAPPARGPPARDFFAR1LMNA | |
| SCHEMBL6818157 | 0.86 | PPARA (0.52) | PPARAPPARGPPARDFFAR1LMNA | |
| SCHEMBL6817538 | 0.83 | PPARG (0.52) | PPARAPPARGPPARDL3MBTL1 | |
| Tesaglitazar SCHEMBL16594 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL3162078 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL13602606 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5368994 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD | |
| Tesaglitazar SCHEMBL600880 | 0.83 | PPARA (1.00) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237857-B1 | NEW PHENALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2004-06-30 | — | — | EP | claimed |