Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLA1 | P09884 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693213 | 0.96 | MEN1 (0.57) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL30372497 | 0.89 | MEN1 (0.73) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6699690 | 0.89 | MEN1 (0.73) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6697171 | 0.87 | MEN1 (0.59) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL7859073 | 0.87 | MEN1 (0.61) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6696197 | 0.86 | MEN1 (0.70) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6693496 | 0.86 | MAPT (0.60) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6697958 | 0.86 | MAPT (0.60) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6698290 | 0.84 | MAPT (0.58) | MEN1KMT2AKCNH2MAPTPOLA1 | |
| SCHEMBL6710712 | 0.84 | KCNH2 (0.84) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140851-B1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2004-09-01 | — | — | EP | disclosed |
| EP-1140851-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6248736-B1 | DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES | PHARMACIA & UPJOHN COMPANY | 2001-06-19 | — | — | US | disclosed |
| WO-2000040563-A1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | disclosed |