SCHEMBL6817020

SCHEMBL6817020

CCOC(=O)C[C@@H]1CCc2cc(OCCc3nc(-c4ccc(Cl)cc4)oc3CCc3ccccc3)ccc21

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.74
PPARA Q07869 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6817017 1.00 PPARG (0.74) PPARGPPARA
SCHEMBL6914184 0.91 PPARG (0.89) PPARGPPARA
SCHEMBL6914186 0.91 PPARG (0.89) PPARGPPARA
SCHEMBL13063616 0.85 PPARG (0.75) PPARGPPARA
SCHEMBL1980817 0.85 PPARG (0.84) PPARGPPARA
SCHEMBL9910128 0.84 PPARG (0.75) PPARGPPARA
SCHEMBL9910338 0.84 PPARG (0.75) PPARGPPARA
SCHEMBL820990 0.84 PPARG (0.70) PPARGPPARA
SCHEMBL821104 0.81 PPARA (0.82) PPARGPPARA
SCHEMBL821119 0.81 PPARA (0.70) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004011446-A1 INDANE, DIHYDROBENZOFURAN, AND TETRAHYDRONAPHTHALENE CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ANTIDIABETICS BAYER PHARMACEUTICALS CORPORATION (US) 2004-02-05 WO disclosed