Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635270 | 0.83 | CRBN (0.53) | CRBNDDB1HTT | |
| SCHEMBL1056468 | 0.81 | MAP3K14 (0.43) | CRBNDDB1 | |
| SCHEMBL30897322 | 0.80 | GAA (0.51) | CRBNDDB1HTT | |
| Hydrochloric Acid SCHEMBL7450491 | 0.78 | GAA (0.50) | CRBNDDB1HTT | |
| SCHEMBL19370852 | 0.77 | POLB (0.56) | CRBNDDB1HTT | |
| SCHEMBL10419931 | 0.77 | CRBN (0.51) | CRBNDDB1HTT | |
| SCHEMBL20206912 | 0.76 | CRBN (0.46) | CRBNDDB1HTT | |
| SCHEMBL21325295 | 0.76 | CRBN (0.46) | CRBNDDB1HTT | |
| SCHEMBL723934 | 0.76 | POLB (0.55) | CRBNDDB1HTT | |
| Trimethylammonium SCHEMBL9196583 | 0.76 | GAA (0.48) | CRBNDDB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |