Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 16/20 | 0.67 |
| ▸ | CDK2 | P24941 | 16/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 13/20 | 0.67 |
| ▸ | CDK1 | P06493 | 4/20 | 0.56 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6821677 | 0.99 | CCNE1 (0.66) | CCNE1CDK2PDGFRACDK1PRKCA | |
| Hydrochloric Acid SCHEMBL6821680 | 0.87 | CDK2 (0.66) | CCNE1CDK2PDGFRACDK1PRKCA | |
| SCHEMBL6817978 | 0.85 | CCNE1 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6817973 | 0.85 | CCNE1 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6821205 | 0.84 | CDK2 (0.73) | CCNE1CDK2PDGFRACDK1CCNE2 | |
| Hydrochloric Acid SCHEMBL6821676 | 0.84 | CDK2 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| SCHEMBL6817936 | 0.84 | CDK2 (0.74) | CCNE1CDK2PDGFRACDK1CCNE2 | |
| SCHEMBL6817943 | 0.84 | CDK2 (0.74) | CCNE1CDK2PDGFRACDK1CCNE2 | |
| Hydrochloric Acid SCHEMBL6821675 | 0.84 | CDK2 (0.69) | CCNE1CDK2CCNE2CCNA2CCNA1 | |
| Hydrochloric Acid SCHEMBL6824019 | 0.84 | CDK2 (0.72) | CCNE1CDK2PDGFRACDK1CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056745-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2004-06-16 | — | — | EP | claimed |