Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790971 | 0.86 | HPGD (0.53) | KCNMA1ASAH1HCAR3KMT2AHPGD | |
| SCHEMBL6819471 | 0.84 | MGAM (0.50) | ASAH1HCAR3KMT2AHPGDMAPT | |
| SCHEMBL534899 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL18206302 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL535029 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL337266 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL534984 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL535094 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL5793440 | 0.82 | ASAH1 (0.66) | ASAH1KMT2AHPGDMAPTALOX15 | |
| SCHEMBL6818351 | 0.82 | MGAM (0.44) | ASAH1HCAR3KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938502-B1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK AS (DK) | 2004-10-06 | — | — | EP | disclosed |
| EP-0938502-A1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK A/S (DK) | 1999-09-01 | — | — | EP | disclosed |
| US-5905140-A | ACYLATING INSULIN, INSULIN ANALOGS, AND INSULIN PRECURSORS ON FREE EPSILON-AMINO GROUP OF LYSINE USING ACTIVATED AMIDE WITH ACYL GROUP IN POLAR SOLVENT IN PRESENCE OF BASE | NOVO NORDISK A/S, NOVO ALLE (DK) | 1999-05-18 | — | — | US | disclosed |
| WO-1998002460-A1 | SELECTIVE ACYLATION METHOD | NOVO NORDISK A/S (DK) | 1998-01-22 | — | — | WO | disclosed |