Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | STK16 | O75716 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | STK3 | Q13188 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818175 | 0.92 | ALB (0.36) | ALBPDE10AGSK3AGSK3BPORCN | |
| SCHEMBL6817836 | 0.90 | ALB (0.38) | ALBPDE10AGSK3AGSK3BHIF1A | |
| SCHEMBL6821949 | 0.90 | ALB (0.37) | ALBPDE10AGSK3AGSK3BPORCN | |
| SCHEMBL6818941 | 0.87 | ALB (0.37) | ALBPDE10AGSK3AGSK3BPPARG | |
| SCHEMBL6819350 | 0.85 | HIF1A (0.39) | ALBGSK3AGSK3BHIF1APOLB | |
| SCHEMBL6818579 | 0.83 | HIF1A (0.38) | ALBGSK3AGSK3BHIF1ATP53 | |
| SCHEMBL6814223 | 0.83 | HIF1A (0.40) | ALBGSK3AGSK3BHIF1APOLB | |
| SCHEMBL6818723 | 0.82 | EGLN2 (0.38) | ALBHIF1ATP53POLBMAPT | |
| SCHEMBL6818611 | 0.82 | KDM4E (0.37) | ALBPDE10AGSK3AGSK3BHIF1A | |
| SCHEMBL6821275 | 0.81 | HIF1A (0.38) | ALBGSK3AGSK3BHIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |