Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.32 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817465 | 0.97 | GSK3A (0.37) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6821784 | 0.93 | HIF1A (0.38) | GSK3AGSK3BALBKDM4EHSD17B10 | |
| SCHEMBL6818941 | 0.92 | ALB (0.37) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6814844 | 0.92 | STING1 (0.40) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6818843 | 0.91 | PPARG (0.42) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6818408 | 0.89 | STING1 (0.41) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6818175 | 0.87 | ALB (0.36) | GSK3AGSK3BPPARGALBKDM4E | |
| SCHEMBL6818611 | 0.86 | KDM4E (0.37) | GSK3AGSK3BALBKDM4EHSD17B10 | |
| SCHEMBL6818177 | 0.86 | ALB (0.35) | ALBKDM4EHSD17B10HIF1AEIF4EBP1 | |
| SCHEMBL6817639 | 0.85 | ALB (0.36) | GSK3AGSK3BALBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |