SCHEMBL6819207

SCHEMBL6819207

CN1CCC(Oc2cc(NS(=O)(=O)c3cc([N+](=O)[O-])c(Cl)s3)ccc2Cl)C1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 14/20 0.56
HTR6 P50406 1/20 0.39
VCAM1 P19320 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
SCD O00767 1/20 0.35
USP7 Q93009 1/20 0.35
USP47 Q96K76 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6819203 1.00 UTS2R (0.56) UTS2RHTR6VCAM1SMN1; SMN2SCD
SCHEMBL6815846 0.89 UTS2R (0.57) UTS2RHTR6
SCHEMBL6815857 0.89 UTS2R (0.57) UTS2RHTR6
SCHEMBL7132246 0.88 UTS2R (0.52) UTS2RHTR6SCD
SCHEMBL8341476 0.87 UTS2R (0.49) UTS2RHTR6
SCHEMBL5742992 0.85 UTS2R (0.68) UTS2RHTR6SMN1; SMN2
SCHEMBL5742998 0.85 UTS2R (0.68) UTS2RHTR6SMN1; SMN2
SCHEMBL5835192 0.85 UTS2R (0.60) UTS2RVCAM1SMN1; SMN2
SCHEMBL5835185 0.85 UTS2R (0.60) UTS2RVCAM1SMN1; SMN2
SCHEMBL5744180 0.82 UTS2R (0.69) UTS2RHTR6SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043366-A2 SULFONAMIDES SMITHKLINE BEECHAM CORPORATION (US) 2004-05-27 WO disclosed