Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6822476 | 0.91 | HIF1A (0.44) | HIF1ATP53ALBMAPTHTT | |
| SCHEMBL6818898 | 0.90 | TP53 (0.36) | HIF1ATP53ALBNTRK1HTT | |
| SCHEMBL6818535 | 0.89 | KMT2A (0.39) | HIF1ATP53ALBMAPTNTRK1 | |
| SCHEMBL6818353 | 0.89 | DHODH (0.37) | HIF1ATP53ALBNTRK1HTT | |
| SCHEMBL6817481 | 0.89 | S1PR1 (0.36) | HIF1ATP53ALBMAPTCA12 | |
| SCHEMBL6818143 | 0.88 | SMN1; SMN2 (0.38) | HIF1ATP53ALBMAPTNTRK1 | |
| SCHEMBL6818716 | 0.87 | PDE10A (0.36) | HIF1ATP53ALBMAPTNTRK1 | |
| SCHEMBL6818297 | 0.87 | HIF1A (0.45) | HIF1ATP53ALBMAPTCA12 | |
| SCHEMBL6819209 | 0.87 | HIF1A (0.34) | HIF1ATP53ALBMAPTCA12 | |
| SCHEMBL6818271 | 0.87 | DHODH (0.36) | HIF1ATP53ALBNTRK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |