Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820307 | 1.00 | UTS2R (0.59) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820792 | 0.94 | UTS2R (0.57) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820790 | 0.94 | UTS2R (0.57) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820332 | 0.91 | UTS2R (0.62) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820324 | 0.91 | UTS2R (0.62) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820351 | 0.89 | UTS2R (0.57) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6820339 | 0.89 | UTS2R (0.57) | UTS2RKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6821116 | 0.89 | UTS2R (0.61) | UTS2RMAPT | |
| SCHEMBL6821111 | 0.89 | UTS2R (0.61) | UTS2RMAPT | |
| SCHEMBL6821133 | 0.88 | UTS2R (0.61) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |