SCHEMBL6820361

SCHEMBL6820361

CC1=C2CC(C)c3cc(C)ccc3N2CCC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 20/20 1.00
SRD5A2 P31213 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6819774 0.87 SRD5A1 (1.00) SRD5A1
SCHEMBL6820061 0.83 SRD5A1 (0.71) SRD5A1SRD5A2
SCHEMBL6819779 0.77 SRD5A1 (0.62) SRD5A1SRD5A2
SCHEMBL6820079 0.76 SRD5A1 (1.00) SRD5A1
SCHEMBL6819198 0.74 SRD5A1 (1.00) SRD5A1SRD5A2
SCHEMBL6820080 0.73 SRD5A1 (0.77) SRD5A1SRD5A2
SCHEMBL28042961 0.68 SRD5A1 (0.50) SRD5A1
SCHEMBL6820238 0.66 SRD5A1 (0.62) SRD5A1
SCHEMBL6822967 0.64 SRD5A1 (0.64) SRD5A1
SCHEMBL6815752 0.64 SRD5A1 (1.00) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1102765-B1 PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES APPLIED RESEARCH SYSTEMS (AN) 2003-09-17 EP claimed
US-6723850-B1 N-ALKYLATION OF THE THIOAMIDE WITH A VINYL KETONE IN PRESENCE OF A STRONG BASE; 6-CHLORO-(1H)-3,4-DIHYDROQUINOLIN-2-THIONE REACTED WITH ETHYL VINYL KETONE APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2004-04-20 US disclosed
EP-1102765-B1 PROCESS FOR THE SYNTHESIS OF (1$i(H))-BENZO C]QUINOLIZIN-3-ONES DERIVATIVES APPLIED RESEARCH SYSTEMS (AN) 2003-09-17 EP disclosed