Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 19/20 | 0.76 |
| ▸ | CDK1 | P06493 | 18/20 | 0.76 |
| ▸ | CCNE1 | P24864 | 18/20 | 0.76 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.74 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.74 |
| ▸ | CDK4 | P11802 | 3/20 | 0.74 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.74 |
| ▸ | CCND1 | P24385 | 3/20 | 0.74 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.74 |
| ▸ | FLT3 | P36888 | 2/20 | 0.74 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.70 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.70 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27459716 | 0.99 | CDK2 (0.75) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6817882 | 0.99 | CDK2 (0.75) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL15947166 | 0.87 | CCNE1 (1.00) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL4314535 | 0.85 | CDK2 (1.00) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL4314539 | 0.85 | CDK2 (1.00) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL15947167 | 0.84 | CDK2 (1.00) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6817884 | 0.84 | CDK2 (0.98) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL6821301 | 0.84 | CDK2 (0.84) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6817891 | 0.84 | CDK2 (0.98) | CDK2CDK1CCNE1CCNE2CCNB2 | |
| SCHEMBL6941836 | 0.84 | CDK2 (0.60) | CDK2CDK1CCNE1CCNE2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056745-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2004-06-16 | — | — | EP | claimed |