Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823505 | 0.92 | UTS2R (0.36) | UTS2RLMNAFFAR4HTTSMN1; SMN2 | |
| SCHEMBL6817492 | 0.90 | UTS2R (0.35) | UTS2RHTTSMN1; SMN2HPGD | |
| SCHEMBL6817378 | 0.90 | UTS2R (0.41) | UTS2RLMNAMEN1KMT2AHTT | |
| SCHEMBL6821387 | 0.88 | UTS2R (0.36) | UTS2RLMNAPKMHTTSMN1; SMN2 | |
| SCHEMBL6821340 | 0.88 | UTS2R (0.36) | UTS2RLMNAFFAR4HTTSMN1; SMN2 | |
| SCHEMBL6820785 | 0.88 | UTS2R (0.36) | UTS2RLMNAMEN1KMT2AFFAR4 | |
| SCHEMBL6821386 | 0.87 | UTS2R (0.36) | UTS2RLMNAFFAR4HTTSMN1; SMN2 | |
| SCHEMBL6823458 | 0.87 | UTS2R (0.36) | UTS2RLMNAHTTSMN1; SMN2 | |
| SCHEMBL6824519 | 0.86 | TP53 (0.37) | UTS2RLMNAMEN1PKMKMT2A | |
| SCHEMBL6820297 | 0.85 | FFAR4 (0.43) | UTS2RLMNAMEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |