Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | TDO2 | P48775 | 4/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | IL1B | P01584 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1598239 | 1.00 | DPP4 (0.45) | DPP4DPP8DPP7CHEK1IDO1 | |
| SCHEMBL1598150 | 0.96 | DPP4 (0.46) | DPP4DPP8DPP7IDO1TDO2 | |
| SCHEMBL1598152 | 0.96 | DPP4 (0.46) | DPP4DPP8DPP7IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL3613927 | 0.95 | DPP4 (0.45) | DPP4DPP8DPP7IDO1TDO2 | |
| SCHEMBL1598339 | 0.82 | SLC6A4 (0.43) | CHEK1IDO1TDO2PRMT5IRAK4 | |
| SCHEMBL1598340 | 0.82 | SLC6A4 (0.43) | CHEK1IDO1TDO2PRMT5IRAK4 | |
| SCHEMBL15739611 | 0.79 | EGLN2 (0.51) | DPP4DPP8DPP7CHEK1 | |
| SCHEMBL15229670 | 0.79 | DPP4 (0.39) | DPP4DPP8DPP7IL1B | |
| SCHEMBL3385188 | 0.77 | IDH1 (0.39) | DPP4DPP8DPP7 | |
| SCHEMBL3385179 | 0.77 | IDH1 (0.39) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041807-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-05-21 | — | — | WO | disclosed |