Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 19/20 | 0.81 |
| ▸ | CCNE1 | P24864 | 18/20 | 0.81 |
| ▸ | CDK1 | P06493 | 16/20 | 0.81 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.69 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.69 |
| ▸ | CDK4 | P11802 | 3/20 | 0.69 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.69 |
| ▸ | CCND1 | P24385 | 3/20 | 0.69 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.69 |
| ▸ | FLT3 | P36888 | 3/20 | 0.69 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.67 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.59 |
| ▸ | CDK7 | P50613 | 2/20 | 0.59 |
| ▸ | CDK9 | P50750 | 2/20 | 0.59 |
| ▸ | CCNH | P51946 | 2/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.59 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821242 | 1.00 | CDK2 (0.81) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6820858 | 0.99 | CDK2 (0.80) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6820860 | 0.99 | CDK2 (0.80) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL6821247 | 0.92 | CDK2 (0.79) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL6821245 | 0.92 | CDK2 (0.79) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6824198 | 0.91 | CDK2 (0.78) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| Hydrochloric Acid SCHEMBL6820821 | 0.91 | CDK2 (0.78) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL6821568 | 0.90 | CDK2 (0.82) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL6821563 | 0.90 | CDK2 (0.82) | CDK2CCNE1CDK1CCNE2CCNB2 | |
| SCHEMBL15118133 | 0.89 | CDK2 (0.98) | CDK2CCNE1CDK1CCNE2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056745-B1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMA INC (US) | 2004-06-16 | — | — | EP | claimed |