Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819209 | 0.98 | HIF1A (0.34) | HIF1AALBCA12CA1CA7 | |
| SCHEMBL6821755 | 0.93 | HIF1A (0.35) | HIF1AALBTP53RXFP1POLB | |
| SCHEMBL6821300 | 0.91 | ALB (0.33) | ALBTP53POLBMAPT | |
| SCHEMBL6819385 | 0.91 | ALB (0.33) | ALBTP53POLBMAPT | |
| SCHEMBL6819494 | 0.91 | ALB (0.33) | HIF1AALBSIRT2ITK | |
| SCHEMBL6818876 | 0.90 | ALB (0.32) | ALBTP53 | |
| SCHEMBL6818790 | 0.90 | ALB (0.32) | ALBTP53 | |
| SCHEMBL6817342 | 0.90 | ALB (0.32) | HIF1AALBTP53SIRT2F10 | |
| SCHEMBL6819369 | 0.90 | ALB (0.33) | ALBTP53POLBMAPT | |
| SCHEMBL6818936 | 0.89 | ITK (0.32) | HIF1AALBITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |