Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821796 | 0.93 | HTT (0.42) | TSHRMAPK1HTTALBGPR6 | |
| SCHEMBL6833979 | 0.92 | HTT (0.52) | TSHRMAPK1HTTALBGPR6 | |
| SCHEMBL6830277 | 0.89 | ALB (0.45) | MAPK1HTTALBKMT2AMEN1 | |
| SCHEMBL6818779 | 0.85 | ALB (0.51) | TSHRMAPK1HTTALBGPR6 | |
| SCHEMBL6819583 | 0.83 | ALB (0.53) | TSHRMAPK1HTTALBKMT2A | |
| SCHEMBL6830175 | 0.82 | ALB (0.46) | ALBKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6817870 | 0.82 | ALB (0.51) | TSHRMAPK1HTTALBKMT2A | |
| SCHEMBL6821690 | 0.82 | ALB (0.49) | TSHRMAPK1HTTALBKMT2A | |
| SCHEMBL6932502 | 0.81 | ALB (0.54) | TSHRMAPK1ALBKMT2AMEN1 | |
| SCHEMBL6930797 | 0.81 | ALB (0.53) | TSHRMAPK1ALBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |