Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Miglitol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 9/20 | 1.00 |
| ▸ | MGAM known ✓ | O43451 | 3/20 | 1.00 |
| ▸ | GBA1 | P04062 | 5/20 | 1.00 |
| ▸ | SI | P14410 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | LCT | P09848 | 1/20 | 1.00 |
| ▸ | AGL | P35573 | 3/20 | 0.88 |
| ▸ | GBA2 | Q9HCG7 | 13/20 | 0.68 |
| ▸ | UGCG | Q16739 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Miglitol SCHEMBL15669407 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL9207953 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL7862967 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL5727959 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL20402709 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL6545551 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL23892585 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL15269512 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL22593 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 | |
| Miglitol SCHEMBL25887976 | 1.00 | GAA (1.00) | GAAGBA1MGAMSITDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4483376-A1 | MEASUREMENT, DIAGNOSIS, TREATMENT AND MANAGEMENT OF METABOLIC SYNDROME | García Sada, Fernando (MX) | 2025-01-01 | — | — | EP | claimed |
| CN-118922890-A | Measurement, diagnosis, treatment and management of metabolic syndrome | 费尔南多·加西亚·萨达 | 2024-11-08 | — | — | CN | claimed |
| WO-2023161832-A1 | MEASUREMENT, DIAGNOSIS, TREATMENT AND MANAGEMENT OF METABOLIC SYNDROME | GARCIA SADA FERNANDO (MX) | 2023-08-31 | — | — | WO | claimed |
| US-20230266340-A1 | Measurement, Diagnosis, Treatment and Management of Metabolic Syndrome | SILTI AG (CH) | 2023-08-24 | — | — | US | claimed |
| CN-113549612-A | Immobilized double enzyme and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-10-26 | — | — | CN | claimed |
| EP-0425929-B1 | Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates | BAYER AG (DE) | 1995-12-06 | — | — | EP | claimed |
| US-5071990-A | PREPARATION OF INTERMEDIATES AND THE SYNTHESIS OF N-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-3,4,5-TRIHYDROXYPIPERIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | claimed |
| EP-0425929-A1 | Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates | BAYER AG (DE) | 1991-05-08 | — | — | EP | claimed |
| JP-3153666-A | — | — | None | — | — | JP | disclosed |
| JP-3153666-A | — | — | None | — | — | JP | disclosed |
| EP-4646931-A9 | BIODEGRADABLE IMINOSUGARS AND AMINO CYCLITOL GLYCOSIDES INHIBITING ALPHA-GLUCOSIDASE WITH SYNERGISTIC INSECTICIDE OR ACARICIDE ACTIVITY OR BOTH | Francisco Aragon S.L.U (ES) | 2025-12-24 | — | — | EP | disclosed |
| EP-4646931-A1 | BIODEGRADABLE IMINOSUGARS AND AMINO CYCLITOL GLYCOSIDES INHIBITING ALPHA-GLUCOSIDASE WITH SYNERGISTIC INSECTICIDE OR ACARICIDE ACTIVITY OR BOTH | Francisco Aragon S.L.U (ES) | 2025-11-12 | — | — | EP | disclosed |
| EP-4483376-A1 | MEASUREMENT, DIAGNOSIS, TREATMENT AND MANAGEMENT OF METABOLIC SYNDROME | García Sada, Fernando (MX) | 2025-01-01 | — | — | EP | disclosed |
| CN-118922890-A | Measurement, diagnosis, treatment and management of metabolic syndrome | 费尔南多·加西亚·萨达 | 2024-11-08 | — | — | CN | disclosed |
| US-5071990-A | PREPARATION OF INTERMEDIATES AND THE SYNTHESIS OF N-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-3,4,5-TRIHYDROXYPIPERIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| JP-H03153666-A | PREPARATION OF INTERMEDIATE AND SYNTHESIS OF N-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-3,4,5-TRIHYDROXYPIPERIDINE | BAYER AG | 1991-07-01 | — | — | JP | disclosed |
| JP-H03153666-A | PREPARATION OF INTERMEDIATE AND SYNTHESIS OF N-(2-HYDROXYETHYL)-2-HYDROXYMETHYL-3,4,5-TRIHYDROXYPIPERIDINE | BAYER AG | 1991-07-01 | — | — | JP | disclosed |
| EP-0425929-A1 | Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0425929-A1 | Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |
| EP-0425929-A1 | Process for the preparation of N-(2-hydroxyethyl)-2-hydroxymethyl-3,4,5-trihydroxy-piperidine and of intermediates | BAYER AG (DE) | 1991-05-08 | — | — | EP | disclosed |