Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182536 | 1.00 | CNR1 (0.80) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL5184657 | 1.00 | CNR1 (0.80) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL17547704 | 0.91 | CNR1 (0.66) | CNR1 | |
| SCHEMBL7645975 | 0.89 | CNR1 (1.00) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL27641178 | 0.89 | CNR1 (1.00) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL18125196 | 0.84 | CNR1 (0.63) | CNR1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18125122 | 0.84 | CNR1 (0.63) | CNR1ALDH1A1MEN1KMT2AMAPT | |
| Monoethanolamine SCHEMBL27906482 | 0.84 | CNR1 (0.90) | CNR1ALDH1A1TRPV1MEN1BLM | |
| SCHEMBL5696743 | 0.84 | CNR1 (0.57) | CNR1ALDH1A1HPGDMEN1BLM | |
| SCHEMBL5151784 | 0.83 | EPHX2 (0.59) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004034968-A2 | COMBINATION THERAPY FOR CONTROLLING APPETITES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-04-29 | — | — | WO | disclosed |