Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.59 |
| ▸ | PPARA | Q07869 | 12/20 | 0.59 |
| ▸ | PTGES | O14684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819715 | 1.00 | PPARG (0.59) | PPARGPPARAPTGESALOX5ESR1 | |
| SCHEMBL6819587 | 1.00 | PPARG (0.59) | PPARGPPARAPTGESALOX5ESR1 | |
| SCHEMBL6819104 | 0.93 | PPARG (0.59) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6819491 | 0.93 | PPARG (0.69) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6819926 | 0.93 | PPARG (0.69) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6818869 | 0.93 | PPARG (0.69) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6818705 | 0.86 | PPARA (0.63) | PPARGPPARAPPARD | |
| SCHEMBL6815781 | 0.86 | PPARA (0.69) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6822848 | 0.85 | PPARG (0.56) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6819532 | 0.84 | PPARG (0.61) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237856-B1 | NEW TRI-SUBSTITUTED PHENYL DERIVATIVES AND ANALOGUES | ASTRAZENECA AB (SE) | 2004-05-12 | — | — | EP | claimed |