Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354836 | 0.79 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL2280801 | 0.79 | CYP3A4 (0.52) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL342459 | 0.76 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL29460338 | 0.76 | CYP3A4 (0.48) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL19822055 | 0.76 | CYP3A4 (0.48) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL14102237 | 0.75 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL17162896 | 0.74 | CYP3A4 (0.49) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL17162897 | 0.74 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL30940561 | 0.74 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM | |
| SCHEMBL26964331 | 0.74 | CYP3A4 (0.47) | CYP3A4L3MBTL1TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740774-B1 | REACTING CARBOXAMIDE WITH GLYOXAL MONOACETAL DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | disclosed |
| EP-1078916-B1 | Process for the preparation of N-acylaminoacid esters and N-acylaminoacetals | BASF AG (DE) | 2002-12-11 | — | — | EP | disclosed |
| EP-1078916-A1 | Process for the preparation of N-acylaminoacid esters and N-acylaminoacetals | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |